THE University of Santo Tomas (UST) and Hualien Tzu Chi Hospital and Medical Center in Taiwan have joined forces to conduct a clinical study on telomeres.
This cooperative endeavor signifies a rare clinical trial cooperation between the Philippines and Taiwan but also represents a significant step forward in the health care domain.
Telomeres, often described as the guardians of gene stability, are specialized DNA repeats found at the ends of chromosomes. Their length gradually shortens with each round of chromosome replication, and when they become too short, it triggers cell death.
This unique biological phenomenon allows the length of telomeres to function as a clock for cell division, providing insights into an individual's biological age. Telomeres have also been found to be closely associated with medical conditions, including bone marrow failure, cancer and a range of aging-related diseases.
Under the auspices of the Ministry of Health and Welfare's New Southbound 2.0 Program, Hualien Tzu Chi Hospital has been proactively involved in "New Southbound Medical and Health Cooperation and Industrial Chain Development."
In 2023, the hospital facilitated the establishment of the Department of Traditional Chinese Medicine at Chongren General Hospital in the Philippines.
This strategic move laid the foundation for a multinational clinical trial program, which commenced in mid-October and was carried out in close collaboration with UST. This comprehensive program involves imparting technical training to the Philippine medical and research team and encompasses creating a DNA database to advance the treatment of telomere-related diseases.
The "Telomere Clinical Research and Taiwan Medical Humanities Exchange Workshop" took place at Hualien Tzu Chi Hospital and Medical Center in Hualien City, Taiwan, from Oct. 10 to 16, 2023.
The inaugural ceremony gathered a distinguished assembly of key figures in the medical field.
UST participants in the workshop included Prof. Pia Marie Albano; Associate Prof. Maureen Sabit; Mariella Cielo Cobarrubias, academic staff of the UST Department of Biological Sciences; BS Biology alumnus Jerome Alfred Tabajonda; and Dr. Flordeluna Zapata-Mesina, a hematologic oncologist from UST Hospital.
Dr. Shang-Hsien Yang, who conducted extensive research on bone marrow failure syndrome at Boston Children's Hospital in the United States, played a vital role in establishing the technical platform for telomere-related research.
Under his guidance and with support from Cheng Yoong Pang, deputy director of the Department of Medical Research, and Dr. Liuh-Yow Chen, associate research fellow at the Institute of Molecular Biology, Academia Sinica, this international clinical trial collaboration program with UST became a reality.
Li emphasized the growing importance of cross-border clinical trials by the Ministry of Health and Welfare, citing the rarity of clinical trial cooperation between Taiwan and the Philippines, making this partnership a significant achievement.
Yang expressed optimism that the collaboration and hands-on laboratory work would foster mutual understanding between Taiwan and the Philippines, ensuring smoother cooperation in future clinical trials.
Renowned for her work in cancer research, Albado aspired to uncover the link between telomeres and human health through future clinical trials, with the potential to advance cancer research.
The workshop, spanning several days, included presentations on telomere research, laboratory training and in-depth discussions with the Philippine team. This initiative holds the potential to advance understanding of telomeres and their role in health care, ultimately benefiting patients and medical practitioners worldwide.
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